Minitran (Nitroglycerin)
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Minitran is used for preventing chronic chest pain caused by heart disease. It also may be used for other conditions as determined by your doctor.
Minitran is a nitrate. It works by relaxing (widening) blood vessels. Chest pain occurs when the heart needs more oxygen than it can get. Relaxing blood vessels allows blood to flow more easily. This reduces the heart’s workload and the amount of oxygen needed by the heart.
Most important: Minitran may cause dizziness, lightheadedness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Minitran with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Check with your doctor before you drink alcohol while you are taking Minitran. Drinking alcohol may increase the risk of low blood pressure with Minitran.
Minitran may cause dizziness, lightheadedness, or fainting. Sit down while taking Minitran to avoid falling caused by lightheadedness or dizziness.
Contact your doctor right away if you develop slow heartbeat or new or worsening chest pain after you take Minitran.
Tell your doctor or dentist that you take Minitran before you receive any medical or dental care, emergency care, or surgery.
Minitran may give you daily headaches. This should become less noticeable with time.
Other dosage forms of Minitran (eg, sublingual, or under the tongue, tablets) may not work as well while you are taking Minitran.
Minitran takes about 1 to 2 hours to start working and should not be used for a sudden chest pain attack.
Lab tests, including heart function, blood pressure, and blood electrolyte levels, may be performed while you use Minitran. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
Use Minitran with caution in the ELDERLY; they may be more sensitive to its effects.
Minitran is not recommended for use in CHILDREN; safety and effectiveness in children have not been confirmed.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Minitran while you are pregnant. It is not known if Minitran is found in breast milk. If you are or will be breast-feeding while you are using Minitran, check with your doctor. Discuss any possible risks to your baby.
When used for long periods of time without a break, Minitran may not work as well. This is known as TOLERANCE. Increasing the dose is not effective in managing tolerance to Minitran. Tolerance to other nitrates or nitrites may also occur. Be sure to have a “nitrate-free” period of time each day to help prevent this tolerance. Talk with your doctor if Minitran stops working well. Do not take more than prescribed.
Some people who use Minitran for a long time without a break may develop a physical need to continue taking it. This is known as physical DEPENDENCE. If you use Minitran without a break and then suddenly stop using it, you may get WITHDRAWAL symptoms. These may include chest pain, heart attack, or possibly sudden death. Be sure to have a “nitrate-free” period of time each day; this may help prevent dependence and withdrawal problems.
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