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Niaspan (Niacin)Niaspan Controlled-Release works by reducing LDL (“bad”) cholesterol and triglycerides and increasing HDL (“good”) cholesterol. Niaspan contains niacin, also called nicotinic acid, a B vitamin (vitamin B3). It occurs naturally in plants and animals and is present in many multiple vitamin supplements.

Niaspan lowers cholesterol levels, reducing the risk for a second heart attack, slows or treats hardening of the arteries, and lowers very high serum triglyceride levels. It is used in combination with diet.

Niaspan may also be used for purposes other than those listed in this medication guide.

Most important: Do not take Niaspan if you are allergic to niacin, or if you have severe liver disease, a stomach ulcer, or active bleeding.

Niaspan can cause certain side effects, such as flushing (warmth, itching, redness, or tingly feeling under your skin). These effects can be made worse if you drink alcohol or hot beverages shortly after you take Niaspan. These effects should disappear over time as you keep taking the medication.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Avoid taking colestipol (Colestid) or cholestyramine (Locholest, Prevalite, Questran) at the same time you take Niaspan. If you take either of these other medications, take them at least 4 to 6 hours before or after you take Niaspan.

Niaspan is only part of a complete program of treatment that may also include diet, exercise, weight control, and other medications. Follow your diet, medication, and exercise routines very closely.

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